primary rabbit polyclonal anti ym1 Search Results


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Arg1 expression is reduced in conditional Arg1-null mice after intracranial LPS administration. LPS (4 μg) was injected into the hippocampus of (Arg1fl/fl/LysMcre) and wild-type littermates (Arg1+/+) and mice were allowed to survive for 3 d. Immunohistochemical staining for the general microglia activation marker CD11b (A, B), Arg1 (C, D), and alternative activation marker <t>YM1</t> (E, F) were performed. The boxed area of the CA3 region of the hippocampus is displayed at higher magnification in the insets. Image analyses were performed to measure the percent area of positive stain. LPS induced CD11b expression to the same extent in both genotypes (G); however, conditional Arg1-null mice (Arg1fl/fl/LysMcre) induced minimal Arg1 expression in microglia/macrophages (G) compared with significant induction in wild-type littermates (Arg1+/+). LPS also induced significantly less YM1 expression in Arg1 knock-out mice (Arg1fl/fl/LysMcre) (F, G) compared with wild-type Arg 1-sufficient littermates (Arg1+/+) (E, G). Statistical analyses: two-way ANOVA with Fisher's multiple-comparison as post hoc, *p < 0.05; n = 3.
Rabbit Anti Ym1, supplied by STEMCELL Technologies Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Arg1 expression is reduced in conditional Arg1-null mice after intracranial LPS administration. LPS (4 μg) was injected into the hippocampus of (Arg1fl/fl/LysMcre) and wild-type littermates (Arg1+/+) and mice were allowed to survive for 3 d. Immunohistochemical staining for the general microglia activation marker CD11b (A, B), Arg1 (C, D), and alternative activation marker <t>YM1</t> (E, F) were performed. The boxed area of the CA3 region of the hippocampus is displayed at higher magnification in the insets. Image analyses were performed to measure the percent area of positive stain. LPS induced CD11b expression to the same extent in both genotypes (G); however, conditional Arg1-null mice (Arg1fl/fl/LysMcre) induced minimal Arg1 expression in microglia/macrophages (G) compared with significant induction in wild-type littermates (Arg1+/+). LPS also induced significantly less YM1 expression in Arg1 knock-out mice (Arg1fl/fl/LysMcre) (F, G) compared with wild-type Arg 1-sufficient littermates (Arg1+/+) (E, G). Statistical analyses: two-way ANOVA with Fisher's multiple-comparison as post hoc, *p < 0.05; n = 3.
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Arg1 expression is reduced in conditional Arg1-null mice after intracranial LPS administration. LPS (4 μg) was injected into the hippocampus of (Arg1fl/fl/LysMcre) and wild-type littermates (Arg1+/+) and mice were allowed to survive for 3 d. Immunohistochemical staining for the general microglia activation marker CD11b (A, B), Arg1 (C, D), and alternative activation marker <t>YM1</t> (E, F) were performed. The boxed area of the CA3 region of the hippocampus is displayed at higher magnification in the insets. Image analyses were performed to measure the percent area of positive stain. LPS induced CD11b expression to the same extent in both genotypes (G); however, conditional Arg1-null mice (Arg1fl/fl/LysMcre) induced minimal Arg1 expression in microglia/macrophages (G) compared with significant induction in wild-type littermates (Arg1+/+). LPS also induced significantly less YM1 expression in Arg1 knock-out mice (Arg1fl/fl/LysMcre) (F, G) compared with wild-type Arg 1-sufficient littermates (Arg1+/+) (E, G). Statistical analyses: two-way ANOVA with Fisher's multiple-comparison as post hoc, *p < 0.05; n = 3.
Polyclonal Rabbit Anti Ym 1, supplied by Danaher Inc, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Arg1 expression is reduced in conditional Arg1-null mice after intracranial LPS administration. LPS (4 μg) was injected into the hippocampus of (Arg1fl/fl/LysMcre) and wild-type littermates (Arg1+/+) and mice were allowed to survive for 3 d. Immunohistochemical staining for the general microglia activation marker CD11b (A, B), Arg1 (C, D), and alternative activation marker <t>YM1</t> (E, F) were performed. The boxed area of the CA3 region of the hippocampus is displayed at higher magnification in the insets. Image analyses were performed to measure the percent area of positive stain. LPS induced CD11b expression to the same extent in both genotypes (G); however, conditional Arg1-null mice (Arg1fl/fl/LysMcre) induced minimal Arg1 expression in microglia/macrophages (G) compared with significant induction in wild-type littermates (Arg1+/+). LPS also induced significantly less YM1 expression in Arg1 knock-out mice (Arg1fl/fl/LysMcre) (F, G) compared with wild-type Arg 1-sufficient littermates (Arg1+/+) (E, G). Statistical analyses: two-way ANOVA with Fisher's multiple-comparison as post hoc, *p < 0.05; n = 3.
Rat Anti Mouse Ym1, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Arg1 expression is reduced in conditional Arg1-null mice after intracranial LPS administration. LPS (4 μg) was injected into the hippocampus of (Arg1fl/fl/LysMcre) and wild-type littermates (Arg1+/+) and mice were allowed to survive for 3 d. Immunohistochemical staining for the general microglia activation marker CD11b (A, B), Arg1 (C, D), and alternative activation marker <t>YM1</t> (E, F) were performed. The boxed area of the CA3 region of the hippocampus is displayed at higher magnification in the insets. Image analyses were performed to measure the percent area of positive stain. LPS induced CD11b expression to the same extent in both genotypes (G); however, conditional Arg1-null mice (Arg1fl/fl/LysMcre) induced minimal Arg1 expression in microglia/macrophages (G) compared with significant induction in wild-type littermates (Arg1+/+). LPS also induced significantly less YM1 expression in Arg1 knock-out mice (Arg1fl/fl/LysMcre) (F, G) compared with wild-type Arg 1-sufficient littermates (Arg1+/+) (E, G). Statistical analyses: two-way ANOVA with Fisher's multiple-comparison as post hoc, *p < 0.05; n = 3.
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Arg1 expression is reduced in conditional Arg1-null mice after intracranial LPS administration. LPS (4 μg) was injected into the hippocampus of (Arg1fl/fl/LysMcre) and wild-type littermates (Arg1+/+) and mice were allowed to survive for 3 d. Immunohistochemical staining for the general microglia activation marker CD11b (A, B), Arg1 (C, D), and alternative activation marker <t>YM1</t> (E, F) were performed. The boxed area of the CA3 region of the hippocampus is displayed at higher magnification in the insets. Image analyses were performed to measure the percent area of positive stain. LPS induced CD11b expression to the same extent in both genotypes (G); however, conditional Arg1-null mice (Arg1fl/fl/LysMcre) induced minimal Arg1 expression in microglia/macrophages (G) compared with significant induction in wild-type littermates (Arg1+/+). LPS also induced significantly less YM1 expression in Arg1 knock-out mice (Arg1fl/fl/LysMcre) (F, G) compared with wild-type Arg 1-sufficient littermates (Arg1+/+) (E, G). Statistical analyses: two-way ANOVA with Fisher's multiple-comparison as post hoc, *p < 0.05; n = 3.
Biotinylated Anti Ym1 2, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Danaher Inc goat anti ym 1 igg
Arg1 expression is reduced in conditional Arg1-null mice after intracranial LPS administration. LPS (4 μg) was injected into the hippocampus of (Arg1fl/fl/LysMcre) and wild-type littermates (Arg1+/+) and mice were allowed to survive for 3 d. Immunohistochemical staining for the general microglia activation marker CD11b (A, B), Arg1 (C, D), and alternative activation marker <t>YM1</t> (E, F) were performed. The boxed area of the CA3 region of the hippocampus is displayed at higher magnification in the insets. Image analyses were performed to measure the percent area of positive stain. LPS induced CD11b expression to the same extent in both genotypes (G); however, conditional Arg1-null mice (Arg1fl/fl/LysMcre) induced minimal Arg1 expression in microglia/macrophages (G) compared with significant induction in wild-type littermates (Arg1+/+). LPS also induced significantly less YM1 expression in Arg1 knock-out mice (Arg1fl/fl/LysMcre) (F, G) compared with wild-type Arg 1-sufficient littermates (Arg1+/+) (E, G). Statistical analyses: two-way ANOVA with Fisher's multiple-comparison as post hoc, *p < 0.05; n = 3.
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STEMCELL Technologies Inc rabbit anti-mouse ym1/2
Arg1 expression is reduced in conditional Arg1-null mice after intracranial LPS administration. LPS (4 μg) was injected into the hippocampus of (Arg1fl/fl/LysMcre) and wild-type littermates (Arg1+/+) and mice were allowed to survive for 3 d. Immunohistochemical staining for the general microglia activation marker CD11b (A, B), Arg1 (C, D), and alternative activation marker <t>YM1</t> (E, F) were performed. The boxed area of the CA3 region of the hippocampus is displayed at higher magnification in the insets. Image analyses were performed to measure the percent area of positive stain. LPS induced CD11b expression to the same extent in both genotypes (G); however, conditional Arg1-null mice (Arg1fl/fl/LysMcre) induced minimal Arg1 expression in microglia/macrophages (G) compared with significant induction in wild-type littermates (Arg1+/+). LPS also induced significantly less YM1 expression in Arg1 knock-out mice (Arg1fl/fl/LysMcre) (F, G) compared with wild-type Arg 1-sufficient littermates (Arg1+/+) (E, G). Statistical analyses: two-way ANOVA with Fisher's multiple-comparison as post hoc, *p < 0.05; n = 3.
Rabbit Anti Mouse Ym1/2, supplied by STEMCELL Technologies Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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STEMCELL Technologies Inc rabbit anti mouse ym1 (chi3l3
Arg1 expression is reduced in conditional Arg1-null mice after intracranial LPS administration. LPS (4 μg) was injected into the hippocampus of (Arg1fl/fl/LysMcre) and wild-type littermates (Arg1+/+) and mice were allowed to survive for 3 d. Immunohistochemical staining for the general microglia activation marker CD11b (A, B), Arg1 (C, D), and alternative activation marker <t>YM1</t> (E, F) were performed. The boxed area of the CA3 region of the hippocampus is displayed at higher magnification in the insets. Image analyses were performed to measure the percent area of positive stain. LPS induced CD11b expression to the same extent in both genotypes (G); however, conditional Arg1-null mice (Arg1fl/fl/LysMcre) induced minimal Arg1 expression in microglia/macrophages (G) compared with significant induction in wild-type littermates (Arg1+/+). LPS also induced significantly less YM1 expression in Arg1 knock-out mice (Arg1fl/fl/LysMcre) (F, G) compared with wild-type Arg 1-sufficient littermates (Arg1+/+) (E, G). Statistical analyses: two-way ANOVA with Fisher's multiple-comparison as post hoc, *p < 0.05; n = 3.
Rabbit Anti Mouse Ym1 (Chi3l3, supplied by STEMCELL Technologies Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Arg1 expression is reduced in conditional Arg1-null mice after intracranial LPS administration. LPS (4 μg) was injected into the hippocampus of (Arg1fl/fl/LysMcre) and wild-type littermates (Arg1+/+) and mice were allowed to survive for 3 d. Immunohistochemical staining for the general microglia activation marker CD11b (A, B), Arg1 (C, D), and alternative activation marker YM1 (E, F) were performed. The boxed area of the CA3 region of the hippocampus is displayed at higher magnification in the insets. Image analyses were performed to measure the percent area of positive stain. LPS induced CD11b expression to the same extent in both genotypes (G); however, conditional Arg1-null mice (Arg1fl/fl/LysMcre) induced minimal Arg1 expression in microglia/macrophages (G) compared with significant induction in wild-type littermates (Arg1+/+). LPS also induced significantly less YM1 expression in Arg1 knock-out mice (Arg1fl/fl/LysMcre) (F, G) compared with wild-type Arg 1-sufficient littermates (Arg1+/+) (E, G). Statistical analyses: two-way ANOVA with Fisher's multiple-comparison as post hoc, *p < 0.05; n = 3.

Journal: The Journal of Neuroscience

Article Title: Sustained Arginase 1 Expression Modulates Pathological Tau Deposits in a Mouse Model of Tauopathy

doi: 10.1523/JNEUROSCI.3959-14.2015

Figure Lengend Snippet: Arg1 expression is reduced in conditional Arg1-null mice after intracranial LPS administration. LPS (4 μg) was injected into the hippocampus of (Arg1fl/fl/LysMcre) and wild-type littermates (Arg1+/+) and mice were allowed to survive for 3 d. Immunohistochemical staining for the general microglia activation marker CD11b (A, B), Arg1 (C, D), and alternative activation marker YM1 (E, F) were performed. The boxed area of the CA3 region of the hippocampus is displayed at higher magnification in the insets. Image analyses were performed to measure the percent area of positive stain. LPS induced CD11b expression to the same extent in both genotypes (G); however, conditional Arg1-null mice (Arg1fl/fl/LysMcre) induced minimal Arg1 expression in microglia/macrophages (G) compared with significant induction in wild-type littermates (Arg1+/+). LPS also induced significantly less YM1 expression in Arg1 knock-out mice (Arg1fl/fl/LysMcre) (F, G) compared with wild-type Arg 1-sufficient littermates (Arg1+/+) (E, G). Statistical analyses: two-way ANOVA with Fisher's multiple-comparison as post hoc, *p < 0.05; n = 3.

Article Snippet: Sections were quenched for endogenous peroxidase with 10% methanol, 10% H 2 O 2 , permeabilized (0.2% lysine, 1% Triton X-100 in PBS), and incubated with various primary antibodies: rabbit anti-Tau (H-150; Santa Cruz Biotechnology); rabbit anti-Tau phosphorylated at Ser 199/202 (AnaSpec); rabbit anti-tau phosphorylated at Ser396 (AnaSpec); chicken anti-GFP (Abcam); chicken anti-rat Arg1 (generous gift from Dr. Sydney M. Morris, University of Pittsburg School of Medicine); p62/sqstm1 (ProteinTech); rat anti-mouse CD45, rat anti-mouse CD68, and rat anti-mouse CD11b (AbD Serotec); rabbit anti-IBA-1 (Wako Chemicals); rat anti-HA clone 3F10 (Roche); rabbit anti-YM1 (StemCell Technologies); and biotinylated anti-tau (AT8; Thermo Scientific) overnight at 4°C.

Techniques: Expressing, Injection, Immunohistochemical staining, Staining, Activation Assay, Marker, Knock-Out